Abstract: Some characteristics of a mathematical model simulating the channel deformation of the Brahmaputra River in Bangladesh are described, Under the assumption that the water conveying and sediment carrying capacities in prototype and normalized channels are equal, a single equvialent channel is adopted as a calculating section. Based on analysis and comparison of measured data, some sedimet missing datum are determined. The calculation results of the model agree well with the deformation of the river channel observed during 1965-1989. Then, river channel deformation under different regulations schemes is predicted. Finally, the sensitivity analysis is carried out, and some sensitive factors are pointed out.