Abstract: The study of crop water-fertilizer production function is an important aspect of deficit irrigation theory and will provide the base for increasing use efficiency of soil water and nutrient. The Jensen model and the artificial neural networks (ANN)model are used to describe crop water-fertilizer production function. Both models are validated by field experiments of winter wheat. The results show that both the ANN model and the Jensen model are capable of predicting crop yield on the basis of water and fertilizer used in the field with acceptable precision.