Abstract: Through the analyses of the formation factors causing disaster of the Yangtze River flood,the boundary conditions and its disaste-breeding environment and the carrying body easy to be damaged,this paper devotes to the inevitability of the middle Yangtze River becoming the extreme seriousness of flood disaster in China,analyzes the harnessing of human creature along the river to increase the stability of the river course,thus reducing the risk of flood disaster.But,the tendency of raising the flood stage still exists in the local reaches of the middle Yangtze River,which also increase the dangers of flood disaster and is still the high dangerous basic characteristics in this region.After studying the operation of the Three Gorges Project,new situation of flood protection occurs in the middle Yangtze River.On the one hand,a huge flood control capacity of the Three Gorges Reservoir can retain a large amount of floodwaters,thus greatly reducing the flood disaster in the middle and lower of the Yangtze River.On the other hand,the strong erosion of the river course will make the river regime to change violently,increasing river channel shifting.It is difficult to stabilize bank wall of the local reaches,which also increases the pressure of flood protection.Meanwhile,because of flattening surface slope,there is a tendency to transfer downstream at the risk of flood disaster.In the future,the middle Yangtze River is still the high dangerous region,and it should still be attached great importance to.