Abstract: In order to better cope with the phenomenon of concurrent activity of peak discharge increase and long duration overflow and levee-breach, a comprehensive two-dimensional associate hydrodynamic model theory was proposed by referring to the theory of comprehensive two-dimensional gas chromatography and the model was developed to simulate overflow and levee-breach flood over river channel. Approximate Riemann solution of Roe was used for numerical simulation of interface flux. In the model, coupling river and irrigated area was realized through weir flow equations of overflow and levee-breach, and with dyke broadening taken into account, levee and river-channel mesh was refined to optimize this model by hot start, dry depth and wet depth theory. Moreover, real terrain method was improved by increasing roughness to reflect the influence of dense villages. In this paper, the model was applied to the case of Ningmeng section of Yellow River to simulate overflow and levee-breach flood routing, the calculation results was proved reasonable and reliable, and the flow fields tend to smooth and well-distributed, which preliminarily validated of the accuracy and reliability of the model. The research results was of great significance to river outburst floods detailed simulation, flood risk analysis and flood control decision in this region.