Abstract: Due to the differences in the regional geological and the hydrogeological conditions and the impacts of human activities and climate changes,the process of regional groundwater geochemistry evolution is complex,and controlled by lots of factors.On the basis of the summary of the current major research achievements,this paper gives some reviews about:(1) the principles and methods of analyzing geochemistry system of groundwater;(2) the hydrogeological,isotopic,element analysis methods and applied techniques in the study of groundwater evolution;(3) the geochemical models and the well-known software of simulating groundwater evolution.And in the future,the complex action of natural evolution and human activity,the interaction of groundwater and surface water,the interaction of microbe-water-rock are the hotspots and developing tendencies.In which,the coupling of the physical,chemical and biological actions would be the significant filed in the regional groundwater evolution.