Abstract: In this paper,regional water resources planning is treated as macroeconomic activities. First of all,we introduce a concept of system-macroeconomy-based regional water resources system,on the basis of which a planning system-Multiple-Objective Integrated System(MOIS) is identified. A Macroeconomic Model (MEM)and its submodels act as the core of this system,while a Multiple Objective Analysis (MOA) model takes the position of top model,in which primary relationships in the macroeconomic water resources system are integrated. In addition, forecasting simulation and optimization are also integrated,to make the system a comprehensive tool for regional water resources planning and management.